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QuickView for Calcineurin A1;jsessionid=9F5AD05E80CAD3D814CD9E3AD210A078;jsessionid=CC982852AF34702C1F5EFE636265189A (gene)


Gene Symbol:
Ppp3cb Mus musculus Mus musculus
Full name:
protein phosphatase 3, catalytic subunit, beta isoform
Synonyms:
1110063J16Rik, Calnb, CnAbeta, Cnab, serine/threonine-protein phosphatase 2B catalytic subunit beta isoform, CAM-PRP catalytic subunit, PP2BA beta, calmodulin-dependent calcineurin A subunit beta isoform
Genomic Location:
Chr 14: 21319262-21365766
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster Saccharomyces cerevisiae Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

protein serine/threonine phosphatase activity | cation binding | enzyme binding | phosphatase activity | hydrolase activity | catalytic activity | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | protein heterodimerization activity | ion binding | protein binding | protein phosphatase binding | protein phosphatase 2B binding | protein dimerization activity | phosphoric ester hydrolase activity | calcium ion binding | drug binding | calmodulin-dependent protein phosphatase activity | calmodulin binding | phosphatase binding | metal ion binding | calcium-dependent protein serine/threonine phosphatase activity

GO Biological Process

protein serine/threonine phosphatase activity | leukocyte homeostasis | regulation of T cell mediated immunity | positive regulation of insulin secretion involved in cellular response to glucose stimulus | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | exocytosis | protein dephosphorylation | response to cytokine | regulation of cellular localization | intracellular signal transduction | regulation of localization | establishment of localization | regulation of immune system process | cell differentiation | regulation of T cell mediated cytotoxicity | response to drug | inositol phosphate-mediated signaling | regulation of leukocyte mediated cytotoxicity | regulation of peptide hormone secretion | negative regulation of T cell mediated cytotoxicity | positive regulation of protein secretion | positive regulation of cellular biosynthetic process | cellular process | secretion | lymphocyte differentiation | localization | immune system development | positive regulation of nitrogen compound metabolic process | lymphangiogenesis | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | T cell activation | phosphatase activity | lymph vessel morphogenesis | regulation of peptide secretion | response to stimulus | vasculature development | regulation of insulin secretion | locomotion involved in locomotory behavior | secretion by cell | cardiovascular system development | positive regulation of hormone secretion | regulation of protein transport | positive regulation of RNA biosynthetic process | hemopoiesis | protein modification process | regulation of peptide transport | macromolecule modification | negative regulation of adaptive immune response | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | leukocyte differentiation | locomotion | system development | nitrogen compound metabolic process | multicellular organism development | phosphorus metabolic process | regulation of insulin secretion involved in cellular response to glucose stimulus | lymph vessel development | regulation of hormone levels | regulation of hormone secretion | regulation of gene expression | positive regulation of secretion | positive regulation of cellular metabolic process | phosphoprotein phosphatase activity | regulation of nitrogen compound metabolic process | vesicle-mediated transport | regulation of transcription by RNA polymerase II | second-messenger-mediated signaling | homeostasis of number of cells | locomotory behavior | negative regulation of immune response | phosphorylation | regulated exocytosis | protein phosphorylation | phosphate-containing compound metabolic process | cellular response to drug | cell communication | regulation of cellular metabolic process | lymphocyte homeostasis | heart development | homeostatic process | positive regulation of establishment of protein localization | regulation of RNA metabolic process | positive regulation of transport | positive regulation of peptide hormone secretion | lymphocyte activation | calcium-mediated signaling | T cell differentiation | protein metabolic process | regulation of establishment of protein localization | response to organic substance | positive regulation of insulin secretion | anatomical structure development | metabolic process | regulation of adaptive immune response | regulation of RNA biosynthetic process | calcium ion regulated exocytosis | regulation of secretion | behavior | organic substance metabolic process | animal organ development | regulation of protein secretion | calcineurin-mediated signaling | calcineurin-NFAT signaling cascade | negative regulation of T cell mediated immunity | T cell homeostasis | cell activation | positive regulation of protein transport | anatomical structure formation involved in morphogenesis | regulation of cell communication | dephosphorylation | signaling | regulation of transcription, DNA-templated | cellular protein metabolic process | anatomical structure morphogenesis | developmental process | calmodulin-dependent protein phosphatase activity | cellular protein modification process | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | regulation of protein localization | calcium-dependent protein serine/threonine phosphatase activity | circulatory system development | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

supramolecular fiber | sarcolemma | catalytic complex | sarcomere | cell | myofibril | cytoplasm | intracellular organelle | contractile fiber | protein-containing complex | plasma membrane | T-tubule | protein serine/threonine phosphatase complex | organelle | I band | calcineurin complex | cell periphery | Z disc | intracellular | membrane | supramolecular complex